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FABP4 AntibodyMouse Monoclonal Antibody to FABP4
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AO1324a | 0.1ml 400 ul | 7-10 days | $ 325.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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FABP4 Antibody - Product info | |
| Application | WB
|
| Primary Accession | P15090 |
| Other Accession | NP_001433.1 |
| Reactivity | Human |
| Isotype | Mouse IgG1 |
| Clone Names | 9B8D |
| Calculated MW | 14719 Da |
FABP4 Antibody - Additional info | |
| Gene ID 2167 | |
| Other Names aP2; A-FABP; FABP4 | |
| Target/Specificity Purified recombinant fragment of FABP4 expressed in E. Coli. | |
| Dilution WB~~1:500 - 2000. | |
| Format Purified recombinant fragment of FABP4 expressed in E. Coli. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions FABP4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
FABP4 Antibody - Protein Information | |
| Name FABP4 | |
| Function Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity) | |
| Cellular Location Cytoplasm. Nucleus. Note=Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export (By similarity) | |
FABP4 Antibody - Related products
AP2764a: FABP4 Antibody (N-term)
AP2764b: FABP4 Antibody (C-term)
AP3623a: Phospho-FABP4-pY20 Antibody
RI11904: FABP4 predesign siRNA
BP2764a: FABP4 Antibody (N-term) Blocking Peptide
BP2764b: FABP4 Antibody (C-term) Blocking Peptide
BP2764d: FABP4 Antibody (Y20) Blocking Peptide
BP3623a: Phospho-FABP4-pY20 Antibody Blocking Peptide
AT1986a: FABP4 Antibody (monoclonal) (M05)
FABP4 Antibody - Application data
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Figure 1: Western blot analysis using FABP4 mAb against FABP4-hIgGFc transfected HEK293 cell lysate.
FABP4 Antibody - Research Areas
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BACKGROUND
Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long chain fatty acids, their coenzymes and other hydrophobic ligands and small molecules in the cytoplasm. It is thought that the role of these proteins includes fatty acid uptake, intracellular lipid transport and metabolism. FABP4 encodes the fatty acid binding protein found in adipocytes. FABP4 knockout mice fed a high-fat and high-calorie diet become obese but develop neither insulin resistance nor diabetes, suggesting that this protein might be a link between obesity and insulin resistance and diabetes A related study in humans indicated a similar pattern, suggesting that FABP4 may be a potential therapeutic target in the treatment of these disorders.
REFERENCES
1. Proc. Natl. Acad. Sci. 2006.103:6970?75.
2. Science. 1996. 274:1377?79.
3. Biochemistry. 1997.36(27):8311-7
4. Mol Cell Biochem. 2004.302(1-2):203-13
