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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   FABP2 Antibody   

FABP2 Antibody

Purified Mouse Monoclonal Antibody

  • WB - FABP2 Antibody AO1341a
    Figure 1: Western blot analysis using FABP2 mouse mAb against FABP2-hIgGFc transfected HEK293 (1) cell lysate and LOVO (2) cell lysate.
  • IHC - FABP2 Antibody AO1341a
    Figure 2: Immunohistochemical analysis of paraffin-embedded human Small Intestine tissues using FABP2 mouse mAb
  • IF - FABP2 Antibody AO1341a
    Figure 3: Immunofluorescence analysis of 3T3-L1 cells using FABP2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
  • FC - FABP2 Antibody AO1341a
    Figure 3: Flow cytometric analysis of LOVO cells using FABP2 mouse mAb (green) and negative control (purple).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P12104
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 9A9B7B3
Isotype IgG1
Calculated MW 15kDa
Description The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. Genetic variation in FABP2 may thus contribute to interindividual variation in the response of plasma lipoproteins to different dietary fibres, but the mechanism does not appear to be related to increases in fecal bile acid secretion.
Immunogen Purified recombinant fragment of human FABP2 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 2169
Other Names Fatty acid-binding protein, intestinal, Fatty acid-binding protein 2, Intestinal-type fatty acid-binding protein, I-FABP, FABP2, FABPI
Dilution WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
IF~~1/200 - 1/1000
FC~~1/200 - 1/400
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFABP2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FABP2
Synonyms FABPI
Function FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long- chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.
Cellular Location Cytoplasm.
Tissue Location Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum.
Research Areas
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1. Yamada, K. et al. (1997) Diabetologia. 40(6):706-10 2. Georgopoulos, A. et al. (2000)85(9):3155-60 3. Kim, CH. et al. (2001) Metabolism. 50(4):473-6 4. Fisher, E. et al. (2006) Horm Metab Res. 38(5):341-5

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$ 325.00
Cat# AO1341a
(40 western blots)
Availability: 7-10 days
Bulk Size
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