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ETS1 Antibody

Mouse Monoclonal Antibody to ETS1

  • WB - ETS1 Antibody AO1354b
    Figure 1: Western blot analysis using ETS1 mouse mAb against Jurkat (1), HepG2 (2) and ETS1-hIgGFc transfected HEK293 (3) cell lysate.
  • IHC - ETS1 Antibody AO1354b
    Figure 2: Immunohistochemical analysis of paraffin-embedded human brain tissue (A) and breast tumor (B) uing ETS1 mouse mAb.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P14921
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 10D2
Isotype Mouse IgG1
Calculated MW 50408 Da
Description The ETS1 is a transcription factor known to regulate expression of a number of genes involved in extracellular matrix remodeling. ETS1 is absent from normal gastric epithelium but is expressed in approximately 60% of gastric carcinomas and oral squamous cell carcinomas with a significant correlation to the tumor stage.
Immunogen Purified recombinant fragment of human ETS1 expressed in E. Coli.
Additional Information
Gene ID 2113
Other Names Protein C-ets-1, p54, ETS1, EWSR2
Target/Specificity Purified recombinant fragment of human ETS1 expressed in E. Coli.
Dilution WB~~1:500~~2000
Format Ascitic fluid containing 0.03% sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsETS1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ETS1
Synonyms EWSR2
Function Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion.
Cellular Location Cytoplasm. Nucleus. Note=Delocalizes from nucleus to cytoplasm when coexpressed with isoform Ets-1 p27
Tissue Location Highly expressed within lymphoid cells. Isoforms c-ETS-1A and Ets-1 p27 are both detected in all fetal tissues tested, but vary with tissue type in adult tissues. None is detected in brain or kidney.
Research Areas
Citations (0)

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1. DNA Cell Biol. 2005 Feb;24(2):126-32.

2. Mol Hum Reprod. 2006 Feb;12(2):71-6.

3. J Biol Chem. 2008 Jan 11;283(2):951-62.

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$ 325.00
Cat# AO1354b
(40 western blots)
Availability: 7-10 days
Bulk Size
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