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CSF1 Antibody

Purified Mouse Monoclonal Antibody

  • WB - CSF1 Antibody AO1361a
    Figure 1: Western blot analysis using CSF1 mouse mAb against human recombinant CSF2(AA:18-144) (1) and CSF1(AA:33-496) (2).
  • IHC - CSF1 Antibody AO1361a
    Figure 2: Immunohistochemical analysis of paraffin-embedded human Placenta tissues using anti-CSF1 mouse mAb
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P09603
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 2D10
Isotype IgG1
Calculated MW 60kDa
Description CSF1, also known as MCSF, is a four-α-helicalbundle cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. This protein may be involved in development of the placenta.
Immunogen Purified recombinant fragment of human CSF1 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 1435
Other Names Macrophage colony-stimulating factor 1, CSF-1, M-CSF, MCSF, Lanimostim, Processed macrophage colony-stimulating factor 1, CSF1
Dilution WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCSF1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CSF1
Function Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.
Cellular Location Cell membrane; Single-pass type I membrane protein
Research Areas
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1. J Biol Chem. 1992 Feb 5;267(4):2190-9. 2. FEBS Lett. 1987 Oct 5;222(2):341-4. 3. Mol Reprod Dev. 1997 Jan;46(1):4-10.

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$ 325.00
Cat# AO1361a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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