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PRDM1 Antibody

Purified Mouse Monoclonal Antibody

  • WB - PRDM1 Antibody AO1373a
    Figure 1: Western blot analysis using PRDM1 mouse mAb against Raji (1, 2), L1210 (3) and TPH-1 (4) cell lysate.
  • IHC - PRDM1 Antibody AO1373a
    Figure 2: Immunohistochemical analysis of paraffin-embedded human lung cancer (A) and esophageal cancer (B), showing cytoplasmic localization using CDC2 mouse mAb with DAB staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75626
Reactivity Human, Mouse
Host Mouse
Clonality Monoclonal
Clone Names 5E7
Isotype IgG1
Calculated MW 88kDa
Description PRDM1/Blimp1 is a repressor of beta-interferon gene expression. This action is exerted by binding to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. The transcription of this gene is increased upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.
Immunogen Purified recombinant fragment of human PRDM1 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 639
Other Names PR domain zinc finger protein 1, 2.1.1.-, BLIMP-1, Beta-interferon gene positive regulatory domain I-binding factor, PR domain-containing protein 1, Positive regulatory domain I-binding factor 1, PRDI-BF1, PRDI-binding factor 1, PRDM1, BLIMP1
Dilution WB~~1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPRDM1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRDM1
Synonyms BLIMP1
Function Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene (PubMed:1851123). Drives the maturation of B-lymphocytes into Ig secreting cells (PubMed:12626569).
Cellular Location Nucleus {ECO:0000250|UniProtKB:Q60636}. Cytoplasm
Research Areas
Citations (0)

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1. Nat Cell Biol. 2006 Jun;8(6):623-30. 2. Int J Hematol. 2007 Dec;86(5):429-37. 3. Nat Genet. 2008 Aug;40(8):955-62.

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$ 325.00
Cat# AO1373a
(40 western blots)
Availability: 7-10 days
Bulk Size
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