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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   CDC25C Antibody   

CDC25C Antibody

Purified Mouse Monoclonal Antibody

  • WB - CDC25C Antibody AO1375a
    Figure 1: Western blot analysis using anti-CDC25C mAb against Hela (1), K562 (2), PC-3 (3), HEK293 (4) and Raw264.7 (5) cell lysate.
  • IHC - CDC25C Antibody AO1375a
    Figure 2: Immunohistochemical analysis of paraffin-embedded human Testis tissues using anti-CDC25C mouse mAb
  • FC - CDC25C Antibody AO1375a
    Figure 3: Flow cytometric analysis of PC-2 cells using CDC2 mouse mAb (green) and negative control (purple).
  • ICC - CDC25C Antibody AO1375a
    Figure 2: Immunofluorescence analysis of Hela cells using CDC2 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
  • IF - CDC25C Antibody AO1375a
    Figure 2:Immunofluorescence analysis of Hela cells using CDC2 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P30307
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 1F12
Isotype IgG1
Calculated MW 58kDa
Description Cdc25C is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It has been highly conserved during evolution and it plays a key role in the regulation of cell division. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Cdc25C is mainly expressed in G2 phase. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
Immunogen Purified recombinant fragment of human CDC25C expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 995
Other Names M-phase inducer phosphatase 3,, Dual specificity phosphatase Cdc25C, CDC25C
Dilution WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCDC25C Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDC25C
Function Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity.
Cellular Location Nucleus
Research Areas
Citations (0)

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1. Cancer Cell. 2007 Mar;11(3):275-89. 2. Int J Biochem Cell Biol. 2007;39(9):1707-13. 3. Int J Cancer. 2010 May 1;126(9):2199-210.

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$ 325.00
Cat# AO1375a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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