|Application ||WB, E|
|Description||The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13.|
|Immunogen||Purified recombinant fragment of human CSF2 (aa18-144) expressed in E. Coli. |
|Formulation||Ascitic fluid containing 0.03% sodium azide. |
|Other Names||Granulocyte-macrophage colony-stimulating factor, GM-CSF, Colony-stimulating factor, CSF, Molgramostin, Sargramostim, CSF2, GMCSF|
|Dilution||WB~~1/500 - 1/2000|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CSF2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.|
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Provided below are standard protocols that you may find useful for product applications.
1. Eur Respir J. 2008 Jul;32(1):25-34. 2. Cell. 2008 Aug 8;134(3):496-507. 3. Mol Immunol. 2008 Nov;46(1):37-44.
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