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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   VCAM1 Antibody   

VCAM1 Antibody

Purified Mouse Monoclonal Antibody

  • WB - VCAM1 Antibody AO1398a
    Figure 1: Western blot analysis using VCAM1 mouse mAb against HUVEC (1) and EC (2) cell lysate.
  • IHC - VCAM1 Antibody AO1398a
    Figure 2: Immunohistochemical analysis of paraffin-embedded human lung cancer (A) and colon cancer (B) using VCAM1 mouse mAb with DAB staining.
  • IHC - VCAM1 Antibody AO1398a
    Figure 3: Immunohistochemical analysis of paraffin-embedded human Placenta tissues using VCAM1 mouse mAb
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P19320
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 6G9
Isotype IgG1
Calculated MW 81kDa
Description This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.Tissue specificity: Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue.INVITROGEN: CD106 is expressed on bone marrow stromal cells, myeloid cells, and endothelial cells.
Immunogen Purified recombinant fragment of human VCAM1 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 7412
Other Names Vascular cell adhesion protein 1, V-CAM 1, VCAM-1, INCAM-100, CD106, VCAM1, L1CAM
Dilution WB~~1/500 - 1/2000
IHC~~1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsVCAM1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name VCAM1
Synonyms L1CAM
Function Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue
Research Areas
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1. Cell Adh Migr. 2009 Oct;3(4):369-72. 2. Arthritis Rheum. 2010 Jan;62(1):105-16.

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$ 325.00
Cat# AO1398a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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