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GATA3 Antibody

Purified Mouse Monoclonal Antibody

  • WB - GATA3 Antibody AO1403a
    Figure 1: Western blot analysis using GATA3 mouse mAb against GATA3(AA: full length)-hIgGFc transfected HEK293 cell lysate.
  • IHC - GATA3 Antibody AO1403a
    Figure 2: Immunohistochemical analysis of paraffin-embedded human Small Intestine, muscularis propria tissues using anti-GATA3 mouse mAb
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P23771
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 7B5
Isotype IgG1
Calculated MW 48kDa
Description This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. (provided by RefSeq) Tissue specificity: T-cells and endothelial cells RD: GATA-3 belongs to the GATA family of transcription factors, which bind to the consensus DNA sequence (A/T) GATA (A/G) to control diverse tissue-specific programs of gene expression and morphogenesis. It is widely expressed in mesodermal- and endodermal-derived tissues. GATA-3 has been shown to be an essential regulator for immune cell function, sympathetic neuron development, and the maintenance of the differentiated state in epithelial cells.
Immunogen Purified recombinant fragment of human GATA3 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 2625
Other Names Trans-acting T-cell-specific transcription factor GATA-3, GATA-binding factor 3, GATA3
Dilution WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGATA3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GATA3
Function Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses.
Cellular Location Nucleus.
Tissue Location T-cells and endothelial cells.
Research Areas
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1. Biogerontology. 2009 Oct;10(5):593-604. 2. Arthritis Rheum. 2009 Mar;60(3):750-9.

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$ 325.00
Cat# AO1403a
(40 western blots)
Availability: 7-10 days
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