|Application ||WB, E|
|Description||ETS variant 5,transcription factor of the ETS family,divergent member of the winged helix-turn-helix superfamily,expressed in brain,placenta and other tissues involved in development. Tissue specificity: Ubiquitous. ERM is expressed in Sertoli cells and spermatogonial stem cells (SSCs). Studies on knockout mice have shown that it is required for SSC self-renewal but not differentiation, thus affected mice exhibit progressive germ cell depletion.|
|Immunogen||Purified recombinant fragment of human ETV5 expressed in E. Coli. |
|Formulation||Ascitic fluid containing 0.03% sodium azide.|
|Other Names||ETS translocation variant 5, Ets-related protein ERM, ETV5, ERM|
|Dilution||WB~~1/500 - 1/2000|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ETV5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds to DNA sequences containing the consensus nucleotide core sequence 5'-GGAA.-3'.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
1. Immunity. 2002 Oct;17(4):401-12. 2. Clin Cancer Res. 2004 Nov 1;10(21):7297-303. 3. J Hum Genet. 2009 Dec;54(12):727-31.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.