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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   STAT6 Antibody   

STAT6 Antibody

Purified Mouse Monoclonal Antibody

  • WB - STAT6 Antibody AO1421a
    Figure 1: Western blot analysis using STAT6 mouse mAb against HEK293 (1), NIH/3T3 (2), MCF-7 (3), Raw246.7 (4) and PC-12 (5) cell lysate.
  • IF - STAT6 Antibody AO1421a
    Figure 2: Immunofluorescence analysis of Hela cells using STAT6 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P42226
Reactivity Human, Mouse, Rat, Monkey
Host Mouse
Clonality Monoclonal
Clone Names 7D3
Isotype IgG1
Calculated MW 94kDa
Description STAT6 protein is a transcription factor activated by cytokines, particularly interleukin 4 and IL 13. (STAT6-/-) were found to be deficient in IL 4 mediated functions including Th2 helper T cell differentiation, expression of cell surface markers, T cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL 4 mediated proliferation. STAT6 mRNA has been detected in peripheral bloodlymphocytes, colon, intestine, ovary, prostate,thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response.
Immunogen Purified recombinant fragment of human STAT6 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 6778
Other Names Signal transducer and activator of transcription 6, IL-4 Stat, STAT6
Dilution WB~~1/500 - 1/2000
IF~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSTAT6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name STAT6
Function Carries out a dual function: signal transduction and activation of transcription. Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling.
Cellular Location Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation
Research Areas
Citations (0)

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1. Pediatr Nephrol. 2009 Mar;24(3):489-95. 2. Mol Immunol. 2009 Jun;46(10):2080-9. 3. Am J Hum Genet. 2009 Nov;85(5):628-42.

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$ 325.00
Cat# AO1421a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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