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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   COX4I1 Antibody   

COX4I1 Antibody

Purified Mouse Monoclonal Antibody

  • WB - COX4I1 Antibody AO1448a
    Figure 1: Western blot analysis using COX4I1 mouse mAb against HEK293 (1), A549 (2) and PC12 (3) cell lysate.
  • IF - COX4I1 Antibody AO1448a
    Figure 2: Immunofluorescence analysis of PANC-1 cells using COX4I1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
  • FC - COX4I1 Antibody AO1448a
    Figure 3: Flow cytometric analysis of K562 cells using COX4I1 mouse mAb (blue) and negative control (red).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P13073
Reactivity Human, Mouse, Rat, Monkey
Host Mouse
Clonality Monoclonal
Clone Names 6B3
Isotype IgG1
Calculated MW 19kDa
Description Cytochrome c oxidase (COX) functions as the terminal oxidase of the respiratory chain that uses cytochrome c as an electron donor to drive a proton gradient across the inner mitochondrial membrane. The mammalian COX apoenzyme is a heteromer consisting of three mitochondrial encoded catalytic subunits and several nuclear gene encoded structural subunits. COX contains two iron-coordination sites and two copper-coordination sites. Cytochrome c oxidase IV (COX4) is a nuclear-encoded subunit of COX that may play a role in regulating COX activity. COX4 is expressed ubiquitously in adult human tissue with the strongest levels of expression in the pancreas and moderate expression levels in heart, skeletal muscle and placenta.
Immunogen Purified recombinant fragment of human COX4I1 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 1327
Other Names Cytochrome c oxidase subunit 4 isoform 1, mitochondrial, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit IV isoform 1, COX IV-1, COX4I1, COX4
Dilution WB~~1/500 - 1/2000
IF~~1/200 - 1/1000
FC~~1/200 - 1/400
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCOX4I1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name COX4I1
Synonyms COX4
Function This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Cellular Location Mitochondrion inner membrane.
Tissue Location Ubiquitous.
Research Areas
Citations (0)

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1. Biochim Biophys Acta. 1992 Feb 26;1119(2):218-24. 2. Histochemistry. 1990;94(2):211-5. 3. FEBS Lett. 2000 Jun 30;476(1-2):22-6.

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$ 325.00
Cat# AO1448a
(40 western blots)
Availability: 7-10 days
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