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MATN1 Antibody
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, ICC, E |
|---|---|
| Primary Accession | Q00266 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 5A8 |
| Isotype | IgG1 |
| Calculated MW | 54kDa |
| Description | This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency. |
| Immunogen | Purified recombinant fragment of human MATN1 expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Gene ID | 4143 |
|---|---|
| Other Names | S-adenosylmethionine synthase isoform type-1, AdoMet synthase 1, 2.5.1.6, Methionine adenosyltransferase 1, MAT 1, Methionine adenosyltransferase I/III, MAT-I/III, MAT1A, AMS1, MATA1 |
| Dilution | WB~~1/500 - 1/2000 IF~~1/200 - 1/1000 |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | MATN1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MAT1A |
|---|---|
| Synonyms | AMS1, MATA1 |
| Function | Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate. |
| Tissue Location | Expressed in liver.. |
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Provided below are standard protocols that you may find useful for product applications.
References
1. Biochem J. 1993 Jul 15;293 ( Pt 2):481-6. 2. Am J Hum Genet. 1997 Mar;60(3):540-6. 3. Am J Hum Genet. 2000 Feb;66(2):347-55.
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