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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MTHFR Antibody   

MTHFR Antibody

Purified Mouse Monoclonal Antibody

  • E - MTHFR Antibody AO1554a

    Red: Control Antigen (100ng);
    Purple: Antigen (10ng);
    Green: Antigen (50ng);
    Blue: Antigen (100ng);

  • WB - MTHFR Antibody AO1554a
    Figure 1: Western blot analysis using MTHFR mouse mAb against Rat Heart cell lysate.
  • WB - MTHFR Antibody AO1554a
    Figure 2: Western blot analysis using MTHFR mAb against HEK293 (1) and MTHFR(AA: 339-499)-hIgGFc transfected HEK293 (2) cell lysate.
  • IHC - MTHFR Antibody AO1554a
    Figure 3: Immunohistochemical analysis of paraffin-embedded lung cancer using MTHFR mouse mAb with DAB staining.
  • IHC - MTHFR Antibody AO1554a
    Figure 4: Immunohistochemical analysis of paraffin-embedded intima cancer tissues (left) and prostate tissues (right) using MTHFR mouse mAb with DAB staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P42898
Reactivity Human, Rat
Host Mouse
Clonality Monoclonal
Clone Names 5D3
Isotype IgG1
Calculated MW 75kDa
Description The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
Immunogen Purified recombinant fragment of human MTHFR expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 4524
Other Names Methylenetetrahydrofolate reductase,, MTHFR
Dilution E~~1/10000
WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMTHFR Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Catalyzes the conversion of 5,10- methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co- substrate for homocysteine remethylation to methionine.
Research Areas
Citations (0)

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1. Kardiol Pol. 2008 Dec;66(12):1269-77. 2. Arq Bras Endocrinol Metabol. 2008 Nov;52(8):1374-81.

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$ 385.00
Cat# AO1554a
(40 western blots)
Availability: 7-10 days
Bulk Size
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