|Application ||WB, FC, E|
|Reactivity||Human, Mouse, Rat, Monkey|
|Description||The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date. (provided by RefSeq)|
|Immunogen||Purified recombinant fragment of human FUK expressed in E. Coli. |
|Formulation||Ascitic fluid containing 0.03% sodium azide.|
|Other Names||L-fucose kinase, Fucokinase, 220.127.116.11, FUK|
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FUK Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides.|
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