|Application ||WB, E|
|Description||The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity.|
|Immunogen||Purified recombinant fragment of human GATA5 expressed in E. Coli. |
|Formulation||Ascitic fluid containing 0.03% sodium azide.|
|Other Names||Transcription factor GATA-5, GATA-binding factor 5, GATA5|
WB~~1/500 - 1/2000
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GATA5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor required during cardiovascular development (PubMed:23289003). Plays an important role in the transcriptional program(s) that underlies smooth muscle cell diversity (By similarity). Binds to the functionally important CEF-1 nuclear protein binding site in the cardiac-specific slow/cardiac troponin C transcriptional enhancer (PubMed:25543888).|
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Provided below are standard protocols that you may find useful for product applications.
1. Clin Cancer Res. 2009 Jun 15;15(12):3990-7. 2. World J Gastroenterol. 2010 Mar 14;16(10):1201-8.
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