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GSTM1 Antibody

Purified Mouse Monoclonal Antibody

  • E - GSTM1 Antibody AO1645a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - GSTM1 Antibody AO1645a
    Figure 1: Western blot analysis using GSTM1 mAb against human GSTM1 (AA: 23-181) recombinant protein. (Expected MW is 25.7 kDa)
  • WB - GSTM1 Antibody AO1645a
    Figure 2: Western blot analysis using GSTM1 mouse mAb against Cos7 (1), MCF-7 (2), Jurkat (3), Hela (4), HL7702 (5) and HepG2 (6) cell lysate.
  • IHC - GSTM1 Antibody AO1645a
    Figure 3: Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using GSTM1 mouse mAb with DAB staining.
  • IHC - GSTM1 Antibody AO1645a
    Figure 4: Immunohistochemical analysis of paraffin-embedded liver cancer tissues using GSTM1 mouse mAb with DAB staining.
  • FC - GSTM1 Antibody AO1645a
    Figure 5: Flow cytometric analysis of Jurkat cells using GSTM1 mouse mAb (green) and negative control (red).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P09488
Reactivity Human, Monkey
Host Mouse
Clonality Monoclonal
Clone Names 1H4A4
Isotype IgG1
Calculated MW 26kDa
Description Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.
Immunogen Purified recombinant fragment of human GSTM1 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 2944
Other Names Glutathione S-transferase Mu 1,, GST HB subunit 4, GST class-mu 1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GSTM1, GST1
Dilution E~~1/10000
WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
FC~~1/200 - 1/400
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGSTM1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GSTM1
Synonyms GST1
Function Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Cellular Location Cytoplasm.
Tissue Location Liver (at protein level).
Citations (0)

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1. J Exp Clin Cancer Res. 2009 Apr 1;28:46. 2. Cancer Prev Res (Phila). 2009 Apr;2(4):345-52.

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$ 385.00
Cat# AO1645a
(40 western blots)
Availability: 7-10 days
Bulk Size
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