|Application ||WB, IHC, FC, ICC, E|
|Description||The protein encoded by this gene may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. The encoded protein is secreted and is a member of the BPI/LBP/PLUNC protein superfamily. This gene is found with other members of the superfamily in a cluster on chromosome 20.|
|Immunogen||Purified recombinant fragment of human LPlunc1 expressed in E. Coli. |
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Other Names||BPI fold-containing family B member 1, Long palate, lung and nasal epithelium carcinoma-associated protein 1, Von Ebner minor salivary gland protein, VEMSGP, BPIFB1, C20orf114, LPLUNC1|
WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
IF~~1/200 - 1/1000
FC~~1/200 - 1/400
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LPlunc1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in innate immunity in mouth, nose and lungs. Binds bacterial lipopolysaccharide (LPS) and modulates the cellular responses to LPS.|
|Tissue Location||Detected in duodenum mucosal crypts of cholera patients, near Paneth cells (at protein level). Detected in trachea, nasal septal epithelium and lung|
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Provided below are standard protocols that you may find useful for product applications.
1. Genes Immun. 2009 Apr;10(3):267-72. 2. Histochem Cell Biol. 2010 May;133(5):505-15.
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