|Application ||WB, IHC, E|
|Reactivity||Human, Mouse, Monkey|
|Description||The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of ASS cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.|
|Immunogen||Purified recombinant fragment of human ASS1 expressed in E. Coli. |
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Other Names||Argininosuccinate synthase, 126.96.36.199, Citrulline--aspartate ligase, ASS1, ASS|
WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ASS1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Is indirectly involved in the control of blood pressure.|
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1. Int J Cancer. 2009 Sep 15;125(6):1454-63. 2. Clin Biochem. 2009 Jul;42(10-11):1166-8.
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