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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MSN Antibody   

MSN Antibody

Purified Mouse Monoclonal Antibody

  • E - MSN Antibody AO1688a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - MSN Antibody AO1688a
    Figure 1: Western blot analysis using MSN mAb against human MSN (AA: 292-491) recombinant protein. (Expected MW is 49.2 kDa)
  • WB - MSN Antibody AO1688a
    Figure 2: Western blot analysis using MSN mouse mAb against HeLa (1), A431 (2),Jurkat(3), HEK293(4), and COS7 (5) cell lysate.
  • IHC - MSN Antibody AO1688a
    Figure 3: Immunohistochemical analysis of paraffin-embedded colon tissues using MSN mouse mAb with DAB staining.
  • FC - MSN Antibody AO1688a
    Figure 4: Flow cytometric analysis of Jurkat cells using MSN mouse mAb (green) and negative control (red).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P26038
Reactivity Human, Monkey
Host Mouse
Clonality Monoclonal
Clone Names 2C12
Isotype IgG1
Calculated MW 67.8kDa
Description Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement.
Immunogen Purified recombinant fragment of human MSN expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 4478
Other Names Moesin, Membrane-organizing extension spike protein, MSN
Dilution E~~1/10000
WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
FC~~1/200 - 1/400
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMSN Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MSN
Function Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage.
Cellular Location Cell membrane; Peripheral membrane protein; Cytoplasmic side Cytoplasm, cytoskeleton. Apical cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, microvillus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Phosphorylated form is enriched in microvilli-like structures at apical membrane (By similarity). Increased cell membrane localization of both phosphorylated and non-phosphorylated forms seen after thrombin treatment. {ECO:0000250, ECO:0000269|PubMed:18586956}
Tissue Location In all tissues and cultured cells studied.
Research Areas
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Int J Cancer. 2009 Apr 1;124(7):1614-21. J Biol Chem. 2009 Jan 23;284(4):2419-34.

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$ 385.00
Cat# AO1688a
(40 western blots)
Availability: 7-10 days
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