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THPO Antibody

Purified Mouse Monoclonal Antibody

  • E - THPO Antibody AO1702a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - THPO Antibody AO1702a
    Figure 1: Western blot analysis using THPO mAb against human THPO (AA: 250-303) recombinant protein. (Expected MW is 30 kDa)
  • FC - THPO Antibody AO1702a
    Figure 2: Flow cytometric analysis of MCF-7 cells using THPO mouse mAb (green) and negative control (red).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P40225
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 1B11
Isotype IgG2a
Calculated MW 37.8kDa
Description Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Alternate splicing results in multiple transcript variants of this gene.
Immunogen Purified recombinant fragment of human THPO expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 7066
Other Names Thrombopoietin, C-mpl ligand, ML, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, MGDF, Myeloproliferative leukemia virus oncogene ligand, THPO, MGDF
Dilution E~~1/10000
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTHPO Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms MGDF
Function Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
Cellular Location Secreted.
Research Areas
Citations (0)

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Blood. 2009 Aug 20;114(8):1655-7. Epub 2009 Jun 24. Ann Hepatol. 2008 Jul-Sep;7(3):235-44.

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$ 385.00
Cat# AO1702a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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