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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   HAS3 Antibody   

HAS3 Antibody

Purified Mouse Monoclonal Antibody

  • E - HAS3 Antibody AO1707a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - HAS3 Antibody AO1707a
    Figure 1: Western blot analysis using HAS3 mAb against human HAS3 (AA: 312-364) recombinant protein. (Expected MW is 32 kDa)
  • IHC - HAS3 Antibody AO1707a
    Figure 2: Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using HAS3 mouse mAb with DAB staining.
  • IHC - HAS3 Antibody AO1707a
    Figure 3: Immunohistochemical analysis of paraffin-embedded prostate tissues using HAS3 mouse mAb with DAB staining.
  • FC - HAS3 Antibody AO1707a
    Figure 4: Flow cytometric analysis of HeLa cells using HAS3 mouse mAb (green) and negative control (red).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O00219
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 3C9
Isotype IgG1
Calculated MW 63kDa
Description The protein encoded by this gene is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. This gene is a member of the NODC/HAS gene family. Compared to the proteins encoded by other members of this gene family, this protein appears to be more of a regulator of hyaluronan synthesis. Alternative splicing results in multiple transcript variants.
Immunogen Purified recombinant fragment of human HAS3 expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 3038
Other Names Hyaluronan synthase 3,, Hyaluronate synthase 3, Hyaluronic acid synthase 3, HA synthase 3, HAS3
Dilution E~~1/10000
WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
FC~~1/200 - 1/400
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHAS3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HAS3
Function Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction (By similarity).
Cellular Location Membrane; Multi-pass membrane protein
Research Areas
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BMC Cancer. 2009 May 12;9:143. BMC Cancer. 2010 Sep 27;10:512.

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$ 385.00
Cat# AO1707a
(40 western blots)
Availability: 7-10 days
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