|Application ||WB, IHC, FC, E|
|Reactivity||Human, Mouse, Monkey|
|Description||The protein encoded by this gene belongs to the rab family. Rab4A protein is involved in the regulation of procathepsin L secretion, it was either inhibited by expression of a Rab4A dominant-negative mutant or increased by overexpression of the wild-type Rab4A in human melanoma cells.|
|Immunogen||Purified recombinant fragment of human RAB4A expressed in E. Coli. |
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Other Names||Ras-related protein Rab-4A, RAB4A, RAB4|
WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
FC~~1/200 - 1/400
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RAB4A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Protein transport. Probably involved in vesicular traffic (By similarity).|
|Cellular Location||Membrane; Peripheral membrane protein. Cytoplasm. Note=Generally associated with membranes. Cytoplasmic when phosphorylated by CDK1|
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Provided below are standard protocols that you may find useful for product applications.
1. Biochem J. 2011 Jul 1;437(1):97-107. 2. Int J Cancer. 2011 Jan 1;128(1):192-205.
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