|Application ||WB, E|
|Description||The protein encoded by this gene is a probable basic helix-loop-helix (bHLH) DNA binding protein involved in muscle differentiation. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of autosomal dominant centronuclear myopathy (ADCNM).|
|Immunogen||Purified recombinant fragment of human MYF6 (AA: 85-150) expressed in E. Coli. |
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Other Names||Myogenic factor 6, Myf-6, Class C basic helix-loop-helix protein 4, bHLHc4, Muscle-specific regulatory factor 4, MYF6, BHLHC4, MRF4|
WB~~1/500 - 1/2000
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MYF6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein.|
|Tissue Location||Skeletal muscle.|
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1.J Bone Miner Res. 2009 Dec;24(12):2039-49. 2.J Appl Physiol. 2006 Aug;101(2):531-44.
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