|Application ||WB, FC, E|
|Description||This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma.|
|Immunogen||Purified recombinant fragment of human SCGB1A1 (AA: 26-91) expressed in E. Coli.|
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Other Names||Uteroglobin, Clara cell phospholipid-binding protein, CCPBP, Clara cells 10 kDa secretory protein, CC10, Secretoglobin family 1A member 1, Urinary protein 1, UP-1, UP1, Urine protein 1, SCGB1A1, CC10, CCSP, UGB|
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SCGB1A1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CC10, CCSP, UGB|
|Function||Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.|
|Tissue Location||Clara cells (nonciliated cells of the surface epithelium of the pulmonary airways)|
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1.Transplantation. 2010 Aug 15;90(3):340-2. 2.Neonatology. 2010;97(3):228-34.
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