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human Splunc2 Antibody

Purified Mouse Monoclonal Antibody

     
  • E - human Splunc2 Antibody AO1773a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

    detail
  • WB - human Splunc2 Antibody AO1773a
    Figure 1: Western blot analysis using Splunc2 mAb against human Splunc2 recombinant protein. (Expected MW is 27.6 kDa)
    detail
  • WB - human Splunc2 Antibody AO1773a
    Figure 2: Western blot analysis using Splunc2 mAb against HEK293 (1) and Splunc2 (AA: 16-250)-hIgGFc transfected HEK293 (2) cell lysate.
    detail
  • FC - human Splunc2 Antibody AO1773a
    Figure 3: Flow cytometric analysis of A549 cells using Splunc2 mouse mAb (green) and negative control (red).
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, FC, E
Primary Accession Q96DR5
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 4C7D7
Isotype IgG1
Calculated MW 27kDa
Description SPLUNC2 is one member of PLUNC family, the gene undergoes alternative splicing using two 5' non-coding exons, suggesting that the gene is regulated by alternative promoters.multiple SPLUNC2 isoforms are found in the oral cavity and suggest that these proteins may be differentially regulated in distinct tissues where they may function in the innate immune response. Mucin plugs, mucous and intermediate cells of mucoepidermoid carcinomas were positive for LPLUNC1 and SPLUNC2, but areas composed of epidermoid and clear cells were negative for all PLUNCs. Papillary cystadenocarcinoma was positive for all PLUNCs.
Immunogen Purified recombinant fragment of human Splunc2 (AA: 16-250) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 140683
Other Names BPI fold-containing family A member 2, Parotid secretory protein, PSP, Short palate, lung and nasal epithelium carcinoma-associated protein 2, BPIFA2, C20orf70, SPLUNC2
Dilution E~~1/10000
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautionshuman Splunc2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BPIFA2
Synonyms C20orf70, SPLUNC2
Function Has strong antibacterial activity against P. aeruginosa.
Cellular Location Secreted.
Tissue Location Detected in submandibular gland. Secreted into saliva.
Research Areas
Citations (0)
citation

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References

1.Histochem Cell Biol. 2009 Sep;132(3):339-49. 2.Oral Dis. 2008 Oct;14(7):613-9.

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$ 385.00
Cat# AO1773a
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