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SFTPC Antibody

Purified Mouse Monoclonal Antibody

  • E - SFTPC Antibody AO1788a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - SFTPC Antibody AO1788a
    Figure 1: Western blot analysis using SFTPC mAb against human SFTPC recombinant protein. (Expected MW is 38.4 kDa)
  • WB - SFTPC Antibody AO1788a
    Figure 2: Western blot analysis using SFTPC mAb against HEK293 (1) and SFTPC (AA: 60-180)-hIgGFc transfected HEK293 (2) cell lysate.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P11686
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 5E6A9
Isotype IgG1
Calculated MW 21kDa
Description This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.
Immunogen Purified recombinant fragment of human SFTPC (AA: 60-180 ) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 6440
Other Names Pulmonary surfactant-associated protein C, SP-C, Pulmonary surfactant-associated proteolipid SPL(Val), SP5, SFTPC, SFTP2
Dilution E~~1/10000
WB~~1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSFTPC Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms SFTP2
Function Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces.
Cellular Location Secreted, extracellular space, surface film.
Research Areas
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1.Am J Respir Cell Mol Biol. 2011 Sep;45(3):498-509. 2.J Biol Chem. 2009 Nov 27;284(48):33377-83.

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$ 385.00
Cat# AO1788a
(40 western blots)
Availability: 7-10 days
Bulk Size
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