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GATA6 Antibody

Purified Mouse Monoclonal Antibody

  • E - GATA6 Antibody AO1797a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - GATA6 Antibody AO1797a
    Figure 1: Western blot analysis using GATA6 mAb against human GATA6 recombinant protein. (Expected MW is 32.3 kDa)
  • WB - GATA6 Antibody AO1797a
    Figure 2: Western blot analysis using GATA6 mAb against HEK293 (1) and GATA6 (AA: 491-557)-hIgGFc transfected HEK293 (2) cell lysate.
  • FC - GATA6 Antibody AO1797a
    Figure 4: Flow cytometric analysis of HEK293 cells using GATA6 mouse mAb (green) and negative control (red).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q92908
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 2F10G3
Isotype IgG1
Calculated MW 60kDa
Description This gene is a member of a small family of zinc finger transcription factors that play an important role in the regulation of cellular differentiation and organogenesis during vertebrate development. This gene is expressed during early embryogenesis and localizes to endo- and mesodermally derived cells during later embryogenesis and thereby plays an important role in gut, lung, and heart development. Mutations in this gene are associated with several congenital defects.
Immunogen Purified recombinant fragment of human GATA6 (AA: 491-557) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 2627
Other Names Transcription factor GATA-6, GATA-binding factor 6, GATA6
Dilution E~~1/10000
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGATA6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GATA6
Function Transcriptional activator that regulates SEMA3C and PLXNA2. Thought to be important for regulating terminal differentiation and/or proliferation. Involved in gene regulation specifically in the gastric epithelium. Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity).
Cellular Location Nucleus.
Tissue Location Expressed in heart, gut and gut-derived tissues
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.


1. BMC Cancer. 2012 Jun 6;12:218. 2. Neonatology. 2011;99(3):231-40.

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$ 385.00
Cat# AO1797a
(40 western blots)
Availability: 7-10 days
Bulk Size
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