|Application ||WB, FC, E|
|Description||This gene encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate.|
|Immunogen||Purified recombinant fragment of human ACP5 (AA: 221-325) expressed in E. Coli.|
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Other Names||Tartrate-resistant acid phosphatase type 5, TR-AP, 22.214.171.124, Tartrate-resistant acid ATPase, TrATPase, Type 5 acid phosphatase, ACP5|
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ACP5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in osteopontin/bone sialoprotein dephosphorylation. Its expression seems to increase in certain pathological states such as Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias.|
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This gene encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. ;
1. Clin Chim Acta. 2011 May 12;412(11-12):963-9. 2. Eur J Gynaecol Oncol. 2011;32(6):615-8.
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