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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   ABCC4 Antibody   

ABCC4 Antibody

Purified Mouse Monoclonal Antibody

  • E - ABCC4 Antibody AO1829a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - ABCC4 Antibody AO1829a
    Figure 1: Western blot analysis using ABCC4 mAb against human ABCC4 recombinant protein. (Expected MW is 32.4 kDa)
  • WB - ABCC4 Antibody AO1829a
    Figure 2: Western blot analysis using ABCC4 mAb against HEK293 (1) and ABCC4 (AA: 631-692)-hIgGFc transfected HEK293 (2) cell lysate.
  • FC - ABCC4 Antibody AO1829a
    Figure 3: Flow cytometric analysis of A549 cells using ABCC4 mouse mAb (green) and negative control (red).
  • IHC - ABCC4 Antibody AO1829a
    Figure 4: Immunohistochemical analysis of paraffin-embedded liver cancer tissues using ABCC4 mouse mAb with DAB staining.
  • IHC - ABCC4 Antibody AO1829a
    Figure 5: Immunohistochemical analysis of paraffin-embedded esophagus cancer tissues using ABCC4 mouse mAb with DAB staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O15439
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 6A7H3
Isotype IgG1
Calculated MW 150kDa
Description The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms.
Immunogen Purified recombinant fragment of human ABCC4 (AA: 631-692) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 10257
Other Names Multidrug resistance-associated protein 4, ATP-binding cassette sub-family C member 4, MRP/cMOAT-related ABC transporter, Multi-specific organic anion transporter B, MOAT-B, ABCC4, MRP4
Dilution E~~1/10000
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
IHC~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsABCC4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ABCC4
Synonyms MRP4
Function May be an organic anion pump relevant to cellular detoxification.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Widely expressed, with particularly high levels in prostate, but is barely detectable in liver
Research Areas
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The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. ; ; ; ;


1. Biochem Pharmacol. 2012 Aug 1;84(3):366-73. 2. Arch Dermatol Res. 2012 Jan;304(1):57-63.

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$ 385.00
Cat# AO1829a
(40 western blots)
Availability: 7-10 days
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