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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SERPINA7 Antibody   

SERPINA7 Antibody

Purified Mouse Monoclonal Antibody

  • E - SERPINA7 Antibody AO1858a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - SERPINA7 Antibody AO1858a
    Figure 1: Western blot analysis using SERPINA7 mAb against human SERPINA7 recombinant protein. (Expected MW is 41.4 kDa)
  • WB - SERPINA7 Antibody AO1858a
    Figure 2: Western blot analysis using SERPINA7 mAb against HEK293 (1) and SERPINA7 (AA: 168-302)-hIgGFc transfected HEK293 (2) cell lysate.
  • IF - SERPINA7 Antibody AO1858a
    Figure 3: Immunofluorescence analysis of A431 cells using SERPINA7 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.
  • FC - SERPINA7 Antibody AO1858a
    Figure 4: Flow cytometric analysis of A431 cells using SERPINA7 mouse mAb (green) and negative control (red).
  • IHC - SERPINA7 Antibody AO1858a
    Figure 5: Immunohistochemical analysis of paraffin-embedded liver cancer tissues using SERPINA7 mouse mAb with DAB staining.
  • IHC - SERPINA7 Antibody AO1858a
    Figure 6: Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using SERPINA7 mouse mAb with DAB staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P05543
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 5B11E9
Isotype IgG1
Calculated MW 46.3kDa
Description There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.
Immunogen Purified recombinant fragment of human SERPINA7 (AA: 168-302) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 6906
Other Names Thyroxine-binding globulin, Serpin A7, T4-binding globulin, SERPINA7, TBG
Dilution E~~1/10000
WB~~1/500 - 1/2000
IF~~1/200 - 1/1000
FC~~1/200 - 1/400
IHC~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSERPINA7 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms TBG
Function Major thyroid hormone transport protein in serum.
Cellular Location Secreted.
Tissue Location Expressed by the liver and secreted in plasma.
Research Areas
Citations (0)

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Papilin is an extracellular matrix glycoprotein involved in, thin matrix layers during gastrulation, matrix associated with wandering, phagocytic hemocytes, basement membranes and space-filling matrix during Drosophila development.Determination of its cDNA sequence led to the identification of Caenorhabditis and mammalian papilins. A distinctly conserved 'papilin cassette' of domains at the amino-end of papilins is also the carboxyl-end of the ADAMTS subgroup of secreted, matrix-associated metalloproteinases; this cassette contains one thrombospondin type 1 (TSR) domain, a specific cysteine-rich domain and several partial TSR domains. In vitro, papilin non-competitively inhibits procollagen N-proteinase, an ADAMTS metalloproteinase. ;


1. Gene. 2012 Sep 15;506(2):289-94. 2. Endocr Regul. 2010 Apr;44(2):43-7.

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$ 385.00
Cat# AO1858a
Availability: 7-10 days
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