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CD93 Antibody

Purified Mouse Monoclonal Antibody

  • E - CD93 Antibody AO1870a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - CD93 Antibody AO1870a
    Figure 1: Western blot analysis using CD93 mAb against human CD93 recombinant protein. (Expected MW is 31.7 kDa)
  • WB - CD93 Antibody AO1870a
    Figure 2: Western blot analysis using CD93 mAb against HEK293 (1) and CD93 (AA: 474-535)-hIgGFc transfected HEK293 (2) cell lysate.
  • IHC - CD93 Antibody AO1870a
    Figure 3: Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using CD93 mouse mAb with DAB staining.
  • IHC - CD93 Antibody AO1870a
    Figure 4: Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using CD93 mouse mAb with DAB staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NPY3
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 2F7D11
Isotype IgG1
Calculated MW 68.6kDa
Description The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton.
Immunogen Purified recombinant fragment of human CD93 (AA: 474-535) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 22918
Other Names Complement component C1q receptor, C1q/MBL/SPA receptor, C1qR, C1qR(p), C1qRp, CDw93, Complement component 1 q subcomponent receptor 1, Matrix-remodeling-associated protein 4, CD93, CD93, C1QR1, MXRA4
Dilution E~~1/10000
WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCD93 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD93
Synonyms C1QR1, MXRA4
Function Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Highly expressed in endothelial cells, platelets, cells of myeloid origin, such as monocytes and neutrophils. Not expressed in cells of lymphoid origin
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated. ; ;


1. PLoS One. 2012;7(12):e51647. 2. J Clin Immunol. 2010 Sep;30(5):723-33.

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$ 385.00
Cat# AO1870a
(40 western blots)
Availability: 7-10 days
Bulk Size
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