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Bpifa2 Antibody

Purified Mouse Monoclonal Antibody

     
  • E - Bpifa2 Antibody AO1912a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

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  • WB - Bpifa2 Antibody AO1912a
    Figure 1: Western blot analysis using mSplunc2 mAb against mSplunc2 (AA: 16-169) recombinant protein. (Expected MW is 18.5 kDa)
    detail
  • WB - Bpifa2 Antibody AO1912a
    Figure 2: Western blot analysis using mSplunc2 mAb against HEK293 (1) and mSplunc2 (AA: 16-169)-hIgGFc transfected HEK293 (2) cell lysate.
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  • FC - Bpifa2 Antibody AO1912a
    Figure 3: Flow cytometric analysis of MCF-7 cells using mSplunc2 mouse mAb (green) and negative control (red).
    detail
  • IHC - Bpifa2 Antibody AO1912a
    Figure 4: Immunohistochemical analysis of paraffin-embedded prostate cancer tissues using mSplunc2 mouse mAb with DAB staining.
    detail
  • IHC - Bpifa2 Antibody AO1912a
    Figure 5: Immunohistochemical analysis of paraffin-embedded endometrial cancer tissues using mSplunc2 mouse mAb with DAB staining.
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  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, FC, E
Primary Accession P07743
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 2B4F5
Isotype IgG1
Calculated MW 24.8kd
Description Bpifa2 has strong antibacterial activity against P. aeruginosa.
Immunogen Purified recombinant fragment of mouse mSplunc2 (AA: 16-169) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.
Additional Information
Gene ID 19194
Other Names BPI fold-containing family A member 2, Parotid secretory protein, PSP, Bpifa2, Psp
Dilution E~~1/10000
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
IHC~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsBpifa2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Bpifa2
Synonyms Psp
Function Has strong antibacterial activity against P. aeruginosa.
Cellular Location Secreted.
Tissue Location Predominates in the parotid glands, present in smaller amounts (1/10) in the submaxillary glands and in the sublingual glands, and at lower amount in the pancreas but undetectable in the liver. Found also in lacrimal gland.
Research Areas
Citations (0)
citation

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Background

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. ; ;

References

1.Am J Physiol. 1997 Apr;272(4 Pt 1):G863-71.2.Nucleic Acids Res. 1998 Jun 1;26(11):2761-70.

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$ 385.00
Cat# AO1912a
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