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SSTR3 Antibody

Purified Mouse Monoclonal Antibody

  • E - SSTR3 Antibody AO1919a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - SSTR3 Antibody AO1919a
    Figure 1: Western blot analysis using SSTR3 mAb against human SSTR3 (AA: 1-43) recombinant protein. (Expected MW is 30.2 kDa)
  • WB - SSTR3 Antibody AO1919a
    Figure 2: Western blot analysis using SSTR3 mAb against HEK293 (1) and SSTR3 (AA: 1-43)-hIgGFc transfected HEK293 (2) cell lysate.
  • WB - SSTR3 Antibody AO1919a
    Figure 3: Western blot analysis using SSTR3 mouse mAb against Hela (1), PANC-1 (2), PC-12 (3),SK-N-SH (4), U937 (5) and HepG2 (6) cell lysate.
  • FC - SSTR3 Antibody AO1919a
    Figure 4: Flow cytometric analysis of Hela cells using SSTR3 mouse mAb (green) and negative control (red).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P32745
Reactivity Human, Rat
Host Mouse
Clonality Monoclonal
Clone Names 7H8E5
Isotype IgG1
Calculated MW 45.8kDa
Description This gene encodes a member of the somatostatin receptor protein family. Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This protein is functionally coupled to adenylyl cyclase. Alternate splicing results in multiple transcript variants.
Immunogen Purified recombinant fragment of human SSTR3 (AA: 1-43) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.
Additional Information
Gene ID 6753
Other Names Somatostatin receptor type 3, SS-3-R, SS3-R, SS3R, SSR-28, SSTR3
Dilution E~~1/10000
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSSTR3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SSTR3
Function Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.
Cellular Location Cell membrane; Multi-pass membrane protein. Note=Internalized into endoplasmic vesicles upon somatostatin-stimulation.
Tissue Location Brain, pituitary and pancreas.
Research Areas
Citations (0)

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This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. ; ;


1. J Gastroenterol Hepatol. 2008 Mar;23(3):424-9. 2. Cancer Biol Ther. 2004 Aug;3(8):726-30.

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$ 385.00
Cat# AO1919a
(40 western blots)
Availability: 7-10 days
Bulk Size
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