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MSTN Antibody

Purified Mouse Monoclonal Antibody

  • E - MSTN Antibody AO1921a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - MSTN Antibody AO1921a
    Figure 1: Western blot analysis using MSTN mAb against human MSTN (AA:24-266 ) recombinant protein. (Expected MW is 28.9 kDa)
  • IHC - MSTN Antibody AO1921a
    Figure 2: Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using MSTN mouse mAb with DAB staining.
  • IHC - MSTN Antibody AO1921a
    Figure 3: Immunohistochemical analysis of paraffin-embedded liver cancer tissues using MSTN mouse mAb with DAB staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O14793
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 6E4E6
Isotype IgG2b
Calculated MW 42.8kDa
Description The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth.
Immunogen Purified recombinant fragment of human MSTN (AA:24-266) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.
Additional Information
Gene ID 2660
Other Names Growth/differentiation factor 8, GDF-8, Myostatin, MSTN, GDF8
Dilution E~~1/10000
WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMSTN Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms GDF8
Function Acts specifically as a negative regulator of skeletal muscle growth.
Cellular Location Secreted.
Citations (0)

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The protein encoded by this gene belongs to the inhibitor of DNA binding family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene of this gene is located on chromosome 3. ; ; ;


1. Eur J Endocrinol. 2012 Dec;167(6):873-80. 2. Biochem J. 2012 Aug 15;446(1):23-36.

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$ 385.00
Cat# AO1921a
(40 western blots)
Availability: 7-10 days
Bulk Size
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