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MSTN Antibody

Purified Mouse Monoclonal Antibody

  • E - MSTN Antibody AO1925a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - MSTN Antibody AO1925a
    Figure 1: Western blot analysis using MSTN mAb against human MSTN (AA:24-266 ) recombinant protein. (Expected MW is 28.9 kDa)
  • WB - MSTN Antibody AO1925a
    Figure 2: Western blot analysis using MSTN mouse mAb against LNcap cell lysate.
  • FC - MSTN Antibody AO1925a
    Figure 3: Flow cytometric analysis of LNcap cells using MSTN mouse mAb (green) and negative control (red).
  • IHC - MSTN Antibody AO1925a
    Figure 4: Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using MSTN mouse mAb with DAB staining.
  • IHC - MSTN Antibody AO1925a
    Figure 5: Immunohistochemical analysis of paraffin-embedded liver cancer tissues using MSTN mouse mAb with DAB staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O14793
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 6E4B2
Isotype IgG2b
Calculated MW 42.8kDa
Description The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth.
Immunogen Purified recombinant fragment of human MSTN (AA:24-266) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.
Additional Information
Gene ID 2660
Other Names Growth/differentiation factor 8, GDF-8, Myostatin, MSTN, GDF8
Dilution E~~1/10000
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
IHC~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMSTN Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms GDF8
Function Acts specifically as a negative regulator of skeletal muscle growth.
Cellular Location Secreted.
Citations (0)

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This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus. ; ; ;


1. Eur J Endocrinol. 2012 Dec;167(6):873-80. 2. Biochem J. 2012 Aug 15;446(1):23-36.

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$ 385.00
Cat# AO1925a
(40 western blots)
Availability: 7-10 days
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