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FTL Antibody

Purified Mouse Monoclonal Antibody

  • E - FTL Antibody AO1949a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - FTL Antibody AO1949a
    Figure 1: Western blot analysis using FTL mAb against human FTL (AA: FULL(1-157)) recombinant protein. (Expected MW is 45.5 kDa)
  • WB - FTL Antibody AO1949a
    Figure 2: Western blot analysis using FTL mAb against HEK293 (1) and FTL (AA: FULL(1-157))-hIgGFc transfected HEK293 (2) cell lysate.
  • WB - FTL Antibody AO1949a
    Figure 3: Western blot analysis using FTL mouse mAb against K562 cell lysate.
  • IF - FTL Antibody AO1949a

    Figure 4:Immunofluorescence analysis of A431 cells using FTL mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

  • IHC - FTL Antibody AO1949a
    Figure 5: Immunohistochemical analysis of paraffin-embedded liver cancer tissues using FTL mouse mAb with DAB staining.
  • IHC - FTL Antibody AO1949a
    Figure 6: Immunohistochemical analysis of paraffin-embedded esophageal tissues using FTL mouse mAb with DAB staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P02792
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 8E1E7
Isotype IgG1
Calculated MW 20kDa
Description This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes.
Immunogen Purified recombinant fragment of human FTL (AA: FULL(1-157)) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.
Additional Information
Gene ID 2512
Other Names Ferritin light chain, Ferritin L subunit, FTL
Dilution E~~1/10000
WB~~1/500 - 1/2000
IF~~1/200 - 1/1000
IHC~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFTL Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FTL
Function Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).
Research Areas
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The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. ; ;


1. Free Radic Biol Med. 2012 May 1;52(9):1692-7.2. Neurobiol Dis. 2010 Jan;37(1):77-85.

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$ 385.00
Cat# AO1949a
(40 western blots)
Availability: 7-10 days
Bulk Size
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