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TFF2 Antibody

Purified Mouse Monoclonal Antibody

  • E - TFF2 Antibody AO1998a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - TFF2 Antibody AO1998a
    Figure 1: Western blot analysis using TFF2 mAb against human TFF2 (AA: 20-125) recombinant protein. (Expected MW is 37.3 kDa)
  • WB - TFF2 Antibody AO1998a
    Figure 2: Western blot analysis using TFF2 mAb against HEK293 (1) and TFF2 (AA: 20-125)-hIgGFc transfected HEK293 (2) cell lysate.
  • FC - TFF2 Antibody AO1998a
    Figure 3: Flow cytometric analysis of Hela cells using TFF2 mouse mAb (green) and negative control (red).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q03403
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 4G7C3
Isotype IgG1
Calculated MW 14.3kDa
Description Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.
Immunogen Purified recombinant fragment of human TFF2 (AA: 20-125) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.
Additional Information
Gene ID 7032
Other Names Trefoil factor 2, Spasmolysin, Spasmolytic polypeptide, SP, TFF2, SML1
Dilution E~~1/10000
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTFF2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TFF2
Synonyms SML1
Function Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains (By similarity).
Cellular Location Secreted.
Tissue Location Stomach.
Research Areas
Citations (0)

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1. Peptides. 2013 Aug;46:1-5.2. Oncol Rep. 2012 Apr;27(4):1207-12.

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$ 385.00
Cat# AO1998a
(40 western blots)
Availability: 7-10 days
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