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HDAC10 Antibody

Purified Mouse Monoclonal Antibody

  • E - HDAC10 Antibody AO2001a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - HDAC10 Antibody AO2001a
    Figure 1: Western blot analysis using HDAC10 mAb against human HDAC10 (AA: 18-219) recombinant protein. (Expected MW is 48.6 kDa)
  • WB - HDAC10 Antibody AO2001a
    Figure 2: Western blot analysis using HDAC10 mAb against HEK293 (1) and HDAC10 (AA: 18-219)-hIgGFc transfected HEK293 (2) cell lysate.
  • IHC - HDAC10 Antibody AO2001a
    Figure 3: Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using HDAC10 mouse mAb with DAB staining.
  • IHC - HDAC10 Antibody AO2001a
    Figure 4: Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using HDAC10 mouse mAb with DAB staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q969S8
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 3B6B8
Isotype IgG2a
Calculated MW 71.4kDa
Description The protein encoded by this gene belongs to the histone deacetylase family, members of which deacetylate lysine residues on the N-terminal part of the core histones. Histone deacetylation modulates chromatin structure, and plays an important role in transcriptional regulation, cell cycle progression, and developmental events. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen Purified recombinant fragment of human HDAC10 (AA: 18-219) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.
Additional Information
Gene ID 83933
Other Names Histone deacetylase 10, HD10,, HDAC10
Dilution E~~1/10000
WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHDAC10 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HDAC10
Function Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
Cellular Location Cytoplasm. Nucleus. Note=Excluded from the nucleoli
Tissue Location Ubiquitous. High expression in liver, spleen, pancreas and kidney
Research Areas
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1. J Biol Chem. 2013 Sep 27;288(39):28021-33.2. Biochem Biophys Res Commun. 2007 Nov 23;363(3):776-81.

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$ 385.00
Cat# AO2001a
(40 western blots)
Availability: 7-10 days
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