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CDH17 Antibody

Purified Mouse Monoclonal Antibody

  • E - CDH17 Antibody AO2004a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - CDH17 Antibody AO2004a
    Figure 1: Western blot analysis using CDH17 mAb against human CDH17 (AA: extra(600-707)) recombinant protein. (Expected MW is 37.9 kDa)
  • WB - CDH17 Antibody AO2004a
    Figure 2: Western blot analysis using CDH17 mAb against HEK293 (1) and CDH17 (AA: extra(600-707))-hIgGFc transfected HEK293 (2) cell lysate.
  • IHC - CDH17 Antibody AO2004a
    Figure 3: Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using CDH17 mouse mAb with DAB staining.
  • IHC - CDH17 Antibody AO2004a
    Figure 4: Immunohistochemical analysis of paraffin-embedded colon tissues using CDH17 mouse mAb with DAB staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q12864
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 7D10E1
Isotype IgG1
Calculated MW 92.2kDa
Description This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.
Immunogen Purified recombinant fragment of human CDH17 (AA: extra(600-707)) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.
Additional Information
Gene ID 1015
Other Names Cadherin-17, Intestinal peptide-associated transporter HPT-1, Liver-intestine cadherin, LI-cadherin, CDH17
Dilution E~~1/10000
WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCDH17 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDH17
Function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin.
Research Areas
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1. Cancer Biol Ther. 2013 Mar;14(3):262-70.2. Mod Pathol. 2008 Nov;21(11):1379-86.

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$ 385.00
Cat# AO2004a
(40 western blots)
Availability: 7-10 days
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