|Application ||WB, FC, ICC, E|
|Description||This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia.|
|Immunogen||LHR-29 from ATCC|
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Other Names||Lutropin-choriogonadotropic hormone receptor, LH/CG-R, Luteinizing hormone receptor, LHR, LSH-R, LHCGR, LCGR, LGR2, LHRHR|
WB~~1/500 - 1/2000
IF~~1/200 - 1/1000
FC~~1/200 - 1/400
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LHCGR Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||LCGR, LGR2, LHRHR|
|Function||Receptor for lutropin-choriogonadotropic hormone (PubMed:11847099). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed:11847099).|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Gonadal and thyroid cells.|
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