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CTSD Antibody

Purified Mouse Monoclonal Antibody

  • E - CTSD Antibody AO2040a

    Figure 1:Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - CTSD Antibody AO2040a

    Figure 2:Western blot analysis using CTSD mAb against human CTSD(AA: 1-100) recombinant protein. (Expected MW is 36.6 kDa)

  • IHC - CTSD Antibody AO2040a

    Figure 3:Immunohistochemical analysis of paraffin-embedded esophagus tissues using CTSD mouse mAb with DAB staining.

  • IHC - CTSD Antibody AO2040a

    Figure 4:Immunohistochemical analysis of paraffin-embedded pancreas tissues using CTSD mouse mAb with DAB staining.

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P07339
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 2H4H5
Isotype IgG1
Calculated MW 44.6kDa
Description This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease.
Immunogen Purified recombinant fragment of human CTSD (AA: 1-100) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 1509
Other Names Cathepsin D,, Cathepsin D light chain, Cathepsin D heavy chain, CTSD, CPSD
Dilution E~~1/10000
WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCTSD Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CPSD
Function Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
Cellular Location Lysosome. Melanosome. Secreted, extracellular space. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In aortic samples, detected as an extracellular protein loosely bound to the matrix (PubMed:20551380).
Tissue Location Expressed in the aorta extrcellular space (at protein level).
Research Areas
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Clin Biochem. 2013 Dec;46(18):1808-11.Cancer Lett. 2012 Oct 28;323(2):208-14.

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$ 385.00
Cat# AO2040a
(40 western blots)
Availability: 7-10 days
Bulk Size
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