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TSHB Antibody

Purified Mouse Monoclonal Antibody

     
  • E - TSHB Antibody AO2200a

    Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

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  • WB - TSHB Antibody AO2200a

    Figure 2:Western blot analysis using TSHB mAb against human TSHB (AA: 20-139) recombinant protein. (Expected MW is 16 kDa)

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  • FC - TSHB Antibody AO2200a

    Figure 3:Flow cytometric analysis of Hela cells using TSHB mouse mAb (green) and negative control (red).

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  • IHC - TSHB Antibody AO2200a

    Figure 4:Immunohistochemical analysis of paraffin-embedded liver cancer tissues using TSHB mouse mAb with DAB staining.

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  • IHC - TSHB Antibody AO2200a

    Figure 5:Immunohistochemical analysis of paraffin-embedded pancreas tissues using TSHB mouse mAb with DAB staining.

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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, FC, E
Primary Accession P01222
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 1D12G1
Isotype IgG2b
Calculated MW 15.6kDa
Description The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants.
Immunogen Purified recombinant fragment of human TSHB (AA: 20-139) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 7252
Other Names Thyrotropin subunit beta, Thyroid-stimulating hormone subunit beta, TSH-B, TSH-beta, Thyrotropin beta chain, Thyrotropin alfa, TSHB
Dilution E~~1/10000
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
IHC~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTSHB Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TSHB
Function Indispensable for the control of thyroid structure and metabolism.
Cellular Location Secreted.
Research Areas
Citations (0)
citation

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References

1.Mol Biol Rep. 2012 Dec;39(12):10019-30.2.Thyroid. 2010 Jun;20(6):639-45.

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$ 385.00
Cat# AO2200a
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