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RNLS Antibody

Purified Mouse Monoclonal Antibody

  • E - RNLS Antibody AO2235a

    Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

  • WB - RNLS Antibody AO2235a

    Figure 2:Western blot analysis using RNLS mAb against human RNLS (AA: 68-242) recombinant protein. (Expected MW is 45.7 kDa)

  • WB - RNLS Antibody AO2235a

    Figure 3:Western blot analysis using RNLS mAb against HEK293 (1) and RNLS (AA: 68-242)-hIgGFc transfected HEK293 (2) cell lysate.

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q5VYX0
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 1C11E8
Isotype IgG1
Calculated MW 37.8kDa
Description Renalase is a flavin adenine dinucleotide-dependent amine oxidase that is secreted into the blood from the kidney
Immunogen Purified recombinant fragment of human RNLS (AA: 68-242) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 55328
Other Names Renalase,, Monoamine oxidase-C, MAO-C, alpha-NAD(P)H oxidase/anomerase, RNLS, C10orf59
Dilution E~~1/10000
WB~~1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRNLS Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms C10orf59
Function Catalyzes the oxidation of the less abundant alpha- NAD(P)H isoform to form beta-NAD(P)(+). The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.
Cellular Location Secreted.
Tissue Location Secreted into the blood by the kidney. Highly expressed in the kidney, expressed at lower level in heart, skeletal muscle and small intestine. Its plasma concentration is markedly reduced in patients with end-stage renal disease, as compared with healthy subjects.
Research Areas
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1.Kidney Blood Press Res. 2014;39(1):58-64.2.Ren Fail. 2013;35(5):673-9.

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$ 385.00
Cat# AO2235a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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