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IL1RAPL1 Antibody

Purified Mouse Monoclonal Antibody

  • E - IL1RAPL1 Antibody AO2236a

    Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

  • WB - IL1RAPL1 Antibody AO2236a

    Figure 2:Western blot analysis using IL1RAPL1 mAb against human IL1RAPL1 (AA: 541-694) recombinant protein. (Expected MW is 43.3 kDa)

  • WB - IL1RAPL1 Antibody AO2236a

    Figure 3:Western blot analysis using IL1RAPL1 mAb against HEK293 (1) and IL1RAPL1 (AA: 541-694)-hIgGFc transfected HEK293 (2) cell lysate.

  • WB - IL1RAPL1 Antibody AO2236a

    Figure 4:Western blot analysis using IL1RAPL1 mouse mAb against A431 (1), SK-Hep-1 (2), and HL-7702 (3) cell lysate.

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NZN1
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 2H3C12
Isotype IgG1
Calculated MW 80kDa
Description The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. It is most closely related to interleukin 1 receptor accessory protein-like 2 (IL1RAPL2). This gene and IL1RAPL2 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation. Deletions and mutations in this gene were found in patients with mental retardation. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities.
Immunogen Purified recombinant fragment of human IL1RAPL1 (AA: 541-694) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 11141
Other Names Interleukin-1 receptor accessory protein-like 1, IL-1-RAPL-1, IL-1RAPL-1, IL1RAPL-1, Oligophrenin-4, Three immunoglobulin domain-containing IL-1 receptor-related 2, TIGIRR-2, X-linked interleukin-1 receptor accessory protein-like 1, IL1RAPL1, OPHN4
Dilution E~~1/10000
WB~~1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIL1RAPL1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms OPHN4
Function May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in presynaptic and postsynaptic differentiation and dendritic spine formation in neurons.
Cellular Location Cell membrane; Single-pass type I membrane protein Cytoplasm. Cell projection, axon. Cell projection, dendrite. Note=May localize to the cell body and growth cones of dendrite-like processes.
Tissue Location Detected at low levels in heart, skeletal muscle, ovary, skin, amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra and thalamus. Detected at very low levels in tonsil, prostate, testis, small intestine, placenta, colon and fetal liver.
Research Areas
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1.Autism Res. 2011 Aug;4(4):293-6.2.Am J Med Genet A. 2011 Feb;155A(2):372-9.

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$ 385.00
Cat# AO2236a
(40 western blots)
Availability: 7-10 days
Bulk Size
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