|Application ||WB, FC, E|
|Description||This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells.|
|Immunogen||Purified recombinant fragment of human NES (AA: 419-588 ) expressed in E. Coli.|
|Formulation||Ascitic fluid containing 0.03% sodium azide.|
|Other Names||Nestin, NES|
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NES Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells (By similarity).|
|Tissue Location||CNS stem cells.|
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1.Neoplasma. 2012;59(3):310-5. 2.Eur J Histochem. 2011 Nov 14;55(4):e39.
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