GUCY1A3 Antibody
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, FC, ICC, E |
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Primary Accession | Q02108 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 3G6B2 |
Isotype | IgG1 |
Calculated MW | 77.5kDa |
Description | Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene. |
Immunogen | Purified recombinant fragment of human GUCY1A3 (AA: 22-214) expressed in E. Coli. |
Formulation | Ascitic fluid containing 0.03% sodium azide. |
Gene ID | 2982 |
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Other Names | Guanylate cyclase soluble subunit alpha-3, GCS-alpha-3, 4.6.1.2, GCS-alpha-1, Soluble guanylate cyclase large subunit, GUCY1A3, GUC1A3, GUCSA3, GUCY1A1 |
Dilution | E~~1/10000 WB~~1/500 - 1/2000 IF~~1/200 - 1/1000 FC~~1/200 - 1/400 IHC~~1/200 - 1/1000 |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | GUCY1A3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GUCY1A1 (HGNC:4685) |
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Cellular Location | Cytoplasm. |
Tissue Location | Detected in brain cortex and lung (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
References
1.Mol Endocrinol. 2012 Feb;26(2):292-307. 2.J Biol Inorg Chem. 2011 Dec;16(8):1227-39.
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