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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Mouse Monoclonal Antibody to LGALS1   

Mouse Monoclonal Antibody to LGALS1

Purified Mouse Monoclonal Antibody

     
  • E - Mouse Monoclonal Antibody to LGALS1 AO2356a
    Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
  • WB - Mouse Monoclonal Antibody to LGALS1 AO2356a
    Western blot analysis using LGALS1 mAb against human LGALS1 (AA: 1-135) recombinant protein. (Expected MW is 40.7 kDa)
  • WB - Mouse Monoclonal Antibody to LGALS1 AO2356a
    Western blot analysis using LGALS1 mAb against HEK293 (1) and LGALS1 (AA: 1-135)-hIgGFc transfected HEK293 (2) cell lysate.
  • FC - Mouse Monoclonal Antibody to LGALS1 AO2356a
    Flow cytometric analysis of Hela cells using LGALS1 mouse mAb (green) and negative control (red).
  • IHC - Mouse Monoclonal Antibody to LGALS1 AO2356a
    Immunohistochemical analysis of paraffin-embedded lung cancer tissues using LGALS1 mouse mAb with DAB staining.
  • IHC - Mouse Monoclonal Antibody to LGALS1 AO2356a
    Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using LGALS1 mouse mAb with DAB staining.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, FC, E
Primary Accession P09382
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 1H11C5
Isotype Mouse IgG1
Calculated MW 14.7kDa
Description The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation.;
Immunogen Purified recombinant fragment of human LGALS1 (AA: 1-135) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Application Note ELISA: 1/10000
WB: 1/500 - 1/2000
IHC: 1/200 - 1/1000
FCM: 1/200 - 1/400
Additional Information
Gene ID 3956
Other Names GBP; GAL1
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Monoclonal Antibody to LGALS1 is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LGALS1
Function Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Expressed in placenta, maternal decidua and fetal membranes. Within placenta, expressed in trophoblasts, stromal cells, villous endothelium, syncytiotrophoblast apical membrane and villous stroma. Within fetal membranes, expressed in amnion, chorioamniotic mesenchyma and chorion (at protein level) Expressed in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney and hematopoietic cells
Research Areas
Citations (0)

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References

1.Cancer Sci. 2014 Nov;105(11):1402-10. ; 2.Lung Cancer. 2014 Apr;84(1):73-8. ;

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$ 385.00
Cat# AO2356a
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