|Application ||WB, IHC, FC, ICC, E|
|Description||The protein encoded by this gene catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4,5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion. Two transcript variants encoding different isoforms have been found for this gene.|
|Immunogen||Purified recombinant fragment of human PLD2 (AA: 834-933) expressed in E. Coli.|
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Application Note||ELISA: 1/10000|
WB: 1/500 - 1/2000
IHC: 1/200 - 1/1000
ICC: 1/200 - 1/1000
FCM: 1/200 - 1/400
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Monoclonal Antibody to PLD2 is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May have a role in signal-induced cytoskeletal regulation and/or endocytosis.|
|Cellular Location||Membrane; Peripheral membrane protein|
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1.Exp Mol Med. 2014 Dec 5;46:e124. ; 2.FEBS Lett. 2014 Aug 25;588(17):3251-8.;
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