|Application ||WB, E|
|Description||Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1; MIM 601974) and the selectin CD62L (SELL; MIM 153240) (summary by Weinreich et al., 2009 [PubMed 19592277]).;|
|Immunogen||Purified recombinant fragment of human KLF2 (AA: 251-355) expressed in E. Coli.|
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Application Note||ELISA: 1/10000|
WB: 1/500 - 1/2000
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Monoclonal Antibody to KLF2 is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor that binds to the CACCC box in the promoter of target genes such as HBB/beta globin or NOV and activates their transcription.|
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1.Tumour Biol. 2015 Apr;36(4):3075-84. ; 2.Cell Physiol Biochem. 2013;32(4):931-41.;
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